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Continued research into its molecular targets at a system level will enable the design of more effective arsenic-based anticancer drugs

As a transcription factor, MYC protein strictly responds to and integrates mitogenic and developmental signals into broad changes in gene expression to support cell growth and proliferation (167)

Associations have been shown in Asians with HLA-A 31:01 and carbamazepine induced SJS/TEN (Ferrell and McLeod, 2008

However, in IPF lungs, mutations of lung epithelial restriction genes (SFTPC, SFTPA2 and ABCA3) and abnormal expression of genes such as MUC5B cause lung epithelial mucosal barrier dysfunction (Hancock et al., 2018)

Travensolo et al., 2008